Educational only. Every hazard ratio and 95% confidence interval below is copied from the trial summaries on this site, which cite NEJM papers and sponsor releases. Different end points, populations and follow-up — read across the plot for scale, not for head-to-head comparison. Grey rows did not meet significance or were not formally tested.
Headline end point
Overall survival
HEALER is left out because its OS was not yet mature.
How to read it
A diamond left of the 1.0 line means fewer events in the experimental arm; the horizontal bar is the 95% CI. A bar that crosses 1.0 is not significant.
Smallest headline HRs: DeLLphi-305 OS and DASL-HiCaP MFS (both 0.42). Largest that still met its end point: HARMONi-GI1 OS (0.75).
CLARITY-Gastric 01 is shown twice: the 3L+ OS dual primary was met, the ITT PFS dual primary was not.
DASL-HiCaP OS (0.88) and INTerpath-001 OS (0.77) are immature and not significant; a big MFS or RFS gain is not yet a survival gain.
Oncosphere